Batch 001 - Live Allocation

Next Release: Aug 2026

Vivre Labs

Institutional Longevity

Catalogue
Single-vial Blends · one injection
Clinical Details

- Peptides -

- Single-vial Blends -

- Goals -

- Clinical Reference -

- Guides -

- Integrity -

∞ V-Series Protocol

V-04Popular · Longevity & Cellular

Cellular - Energy & Longevity

Cellular energy and mitochondrial restoration

Quick Takeaways

✓Restores mitochondrial NAD+ pool for cellular bioenergetics

✓Telomerase support and pineal regulation (Epithalon)

✓Mitochondrial-derived peptide signalling (MOTS-c)

TargetsCellular Longevity · Biological Age

Duration6-month foundational program with quarterly re-assessment

Cohort61 active members

Core Compounds

SS-31 50mgMOTS-cEpithalon

How this protocol is run. The components are generally introduced in sequence rather than all at once, and cycled rather than run continuously - the structural and signaling compounds are phased in over a cycle, with the telomere-axis component used in short periodic courses. The specific order, timing, and cycle length are determined by your supervising physician based on your biomarkers and response - not a fixed self-administered schedule. This is educational context, not a dosing instruction.

Batch 001 Allocation

9 of 15 reserved6 open

Monthly

$480 USD/mo

Founding-Member Savings

Standard (Monthly)$480/mo

6-Month Founding Tier$430/mo

Annual savings$600

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Janoshik Verified

HPLC + MS purity, every batch

Independent third-party lab

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COA Per Batch

Lot-level certificates published

Labeled vs actual mg disclosed

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Protocol Reviewed

Clinical reasoning per stack

Phase 1 supervision onboarding

V-04 · Amber · Longevity

Composition

Each compound, and what it does

Every component is individually sourced, third-party verified, and dispensed within physician supervision. Tap any compound for its full clinical reference.

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Clinical Overview

V-04 Explainer · 90 seconds

Video Coming Soon

Clinical explainer · ~90s · Authored by Vivre Labs Medical Board

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Patient Selection

Who This Protocol Is For

A frontier longevity protocol for patients pursuing measurable biological age intervention. The stack targets the mitochondrion as an integrated endpoint - addressing telomere maintenance, mitochondrial membrane integrity, and metabolic signaling rather than isolated aging hallmarks.

CLINICAL INDICATION: Patients pursuing biological age intervention, healthspan extension, mitochondrial dysfunction

Cohort Outcomes · V-04

What members on Cellular - Energy & Longevity report.

n=34 members completing Week 12 of V-04 · Population medians, individual results vary

IGF-1 increase

+55%

Median, baseline → wk 12

hs-CRP reduction

-54%

Systemic inflammation

Biological age delta

-2.1 yrs

Horvath methylation clock retest

Member VL-2026-0201 (M, 55): Biological age (Horvath) shifted from chronological +2.1 to +0.2 years over 16 weeks. CoQ10 restored to optimum.

Outcomes shown reflect cohort medians from members completing 12 weeks on protocol. Individual outcomes depend on baseline biomarkers, adherence, and physician-directed adjustments. Past cohort performance does not guarantee future results.

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Mechanism

How V-04 Works

Frontier longevity protocol targeting the mitochondrial hallmarks of aging. Epithalon for telomerase activation via pineal-hypothalamic axis modulation; MOTS-c for mitochondrial-derived metabolic signaling; SS-31 (Elamipretide) for cardiolipin stabilization and inner mitochondrial membrane restoration.

Where other longevity protocols address individual aging hallmarks, V-04 targets the mitochondrion as the integrated endpoint. SS-31's cardiolipin-binding action supports electron transport chain function. MOTS-c modulates systemic metabolic signaling. Epithalon influences the pineal-hypothalamic axis. Outcomes are tracked via the Horvath methylation clock and other validated biomarkers.

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Formulation

What arrives each month

◇ Multi-Vial Stack

3 separate vials · Separate injections per physician schedule

No pre-blend exists for this composition. Physician determines individual compound timing based on biomarker response - particularly important for V-04, where each compound has distinct mechanism and timing. Available to partner practices on request - not in the Batch 001 direct catalogue.

What's in the box	Specification	Per month
SS-31 (Elamipretide)	50mg vial · 3 vials typical monthly supply (5mg/day)	3×
MOTS-c	40mg vial · ~64mg/mo at 5mg 3×/week	2×
Epithalon	10mg vial · typical cycling allocation	1×

V-04 cohort tracks individual compound responses given the divergent mechanisms.

Vial counts shown are operational transparency - what arrives in the monthly allocation box. Administration frequency, per-administration amounts, and reconstitution method are physician-determined at consultation, not on this page.

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Components

Core Compounds in V-04

Mitochondrial Protectant

SS-31

Elamipretide · 50mg

Cardiolipin Stabilization

View Compound →

Metabolic Signaler

MOTS-c

Mitochondrial-Derived Peptide · 10mg

AMPK Activation / Mitochondrial Homeostasis

View Compound →

Pineal Regulator

Epithalon

Tetrapeptide · 10mg

Telomerase Activation / Circadian Modulation

View Compound →

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Protocol Timeline

Titration Schedule

Wk 1–2

SS-31 5mg/day SubQ (50mg vial)

Structural scaffolding first - stabilize the inner mitochondrial membrane before adding metabolic load. Physician sets dose; 40mg/day is the Barth-trial dose, not the longevity protocol.

Wk 3–6

SS-31 taper to 1mg/day; introduce MOTS-c 5mg 3×/week

SS-31 steps down over 4 weeks as MOTS-c (mitochondrial signaling, 5mg 3×/week) is layered onto the repaired foundation.

Wk 7+ / tail

Epithalon 10mg SubQ daily (Khavinson 10-day course)

Pineal-axis / telomere overlay at the tail end. Short concentrated cycle, then break per Khavinson protocol. Horvath clock retest at month 6.

Optional member add-ons. Members commonly add (as individual compounds, physician-directed): GHK-Cu for general wellness/skin & tissue support, and Semax for cognitive optimization. These are adjuncts, not part of the core V-04 composition.

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Clinical Oversight

Monitoring & Safety

Lab Monitoring

Horvath methylation clock, telomere length, 8-OHdG, CoQ10, lactate/pyruvate ratio

Contraindications

Active malignancy, organ transplant recipients, severe autoimmune conditions

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Patient Bloodwork Guide

Bloodwork for Longevity & Mitochondrial Protocols

Cellular / mitochondrial - SS-31, MOTS-c, Epithalon, NAD+, V-04

These protocols target cellular energy, mitochondrial function, and markers of biological aging. Monitoring here is less about week-to-week safety and more about confirming the protocol is moving the deeper markers it is meant to.

Incremental approach. V-04 is introduced in phases (structural support first, then signaling, then a short telomere overlay) at conservative doses. Re-testing at the 6-month mark is how progress is judged.

Biological-age markers

Horvath methylation clockAn epigenetic estimate of biological age - the headline longevity marker, retested over months.

Telomere lengthTracks cellular aging at the chromosome level.

Mitochondrial & oxidative

Lactate (fasting & post-exercise)Healthy mitochondria clear lactate quickly. A high or slow-clearing level suggests cells are leaning on less-efficient anaerobic energy; a downward trend over time points to improving mitochondrial efficiency.

Lipid-peroxidation markers (MDA, 4-HNE)Signals of oxidative damage to cell membranes. Relevant to SS-31, which works by protecting the mitochondrial membrane lipid (cardiolipin) - a fall in these markers is a sign that structural protection is taking hold.

Fasting insulin & HOMA-IRA measure of how efficiently muscle takes up glucose. Relevant to MOTS-c, which supports muscle glucose uptake via the AMPK pathway - improvement shows as lower fasting insulin and a lower HOMA-IR score.

8-OHdGA marker of oxidative stress / DNA damage.

CoQ10A cofactor your mitochondria use to move electrons and produce energy.

Functional capacity

VO₂max / Zone-2 thresholdThe functional read-out of mitochondrial fitness - measured during graded exercise testing. As mitochondria adapt, the point where your body shifts from burning fat to burning carbohydrate moves, reflecting better aerobic capacity. A physical metric, not a blood test.

Routine safety

Fasting glucose & CMPStandard metabolic and organ-function checks.

When the tests happen

BaselineHorvath clock, telomere length, 8-OHdG, CoQ10, lactate/pyruvate, CMP.

Through the protocolSymptom and energy tracking; routine glucose/CMP.

Month 6Repeat Horvath clock + key markers to judge progress.

Educational only - not medical advice or a dosing instruction. Your physician orders the tests, sets your dose, interprets results, and decides if a protocol is right for you. See the Informed Consent & Disclaimer for full terms.

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Clinical Monitoring Reference

What Your Physician Tracks - and Why

V-04 targets longevity and cellular-aging markers. The reference set below is what a Vivre physician tracks during supervised use - monitoring practice, not a self-administration guide.

Dosing & Frequency

Physician-supervised protocol with periodic review. Dose and frequency are physician-determined - never self-adjusted.

Biomarker	Why It's Monitored	Baseline	Cadence
hs-CRP	Inflammatory aging contribution	Yes	Baseline + periodic
Fasting glucose / insulin	Metabolic-aging surveillance	Yes	Baseline + periodic
Lipid panel	Cardiometabolic risk tracking	Yes	Baseline + periodic
IGF-1	Growth-axis surveillance	Yes	Baseline + periodic
Renal & hepatic panel	Safety surveillance during sustained use	Yes	Periodic
Biological-age markers	Longitudinal trend (where available)	Optional	Periodic

Monitoring practice shown for education. Allocation and dosing are physician-directed after consultation.

This reference describes physician monitoring practice for educational purposes. It is not a prescription, a dosing instruction, or medical advice. Treatment, dosing, and frequency are determined only by a licensed physician in consultation.

Frequently Asked

Common Questions About V-04

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Commonly Paired

Members on V-04 Often Add

Protocol

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Protocol

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Individual peptide

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Individual peptide

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Individual peptide

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READY TO PROCEED

Start with the Biological Audit

The Audit is complimentary for the Batch 001 cohort. Your physician will review your data, confirm protocol suitability, and initiate the V-04 allocation if appropriate.

$480 USD/mo

V-04 · Monthly